产品与服务

中文名称：RMC-6236

中文同义词：RAS-IN-2;泛KRAS抑制剂;化合物RMC-6236;(1S,2S)-N-[(2R,14S,18S)-1-乙基-18,19,20,21-四氢-2-[2-[(1S)-1-甲氧基乙基]-5-(4-甲基-1-哌嗪基)-3-吡啶基]-25,25-二甲基-15,22-二氧代-17H-5,3-([4,2]-ENDO-噻唑丙烷并[1,3]-ENDO-2-哒嗪基甲氧基丙烷)-1H-吲哚-14-基]-2-甲基环丙烷甲酰胺;(1S,2S)-N-[(2R,14S,18S)-1-乙基-18,19,20,21-四氢-2-[2-[(1S)-1-甲氧基乙基]-5-(4-甲基-1-哌嗪基)-3-吡啶基]-25,25-二甲基-15,22-二氧代-17H-5,3-([4,2]-ENDO-噻唑丙烷并[1,3]-ENDO-2-哒嗪基甲氧基丙烷)-1H-吲哚-;RMC-6236RASONMULTI抑制剂;RMC-6236(Daraxonrasib);RMC-6236酶抑制剂

英文名称：RMC6236

英文同义词：RMC6236;N-[21-ethyl-20-[2-(1-methoxyethyl)-5-(4-methylpiperazin-1-yl)pyridin-3-yl]-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetrazapentacyclo[17.5.2.12,5.19,13.022,26]octacosa-1(25),2,5(28),19,22(26),23-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide;(Z)-N-(11-ethyl-12-(2-(1-methoxyethyl)-5-(4-methylpiperazin-1-yl)pyridin-3-yl)-10,10-dimethyl-5,7-dioxo-61,62,63,64,65,66-hexahydro-11H-8-oxa-2(4,2)-thiazola-1(5,3)-indola-6(1,3)-pyridazinacycloundecaphane-4-yl)-Chemicalbook2-methylcyclopropane-1-carboxamide;(1S,2S)-N-[(2R,14S,18S)-1-Ethyl-18,19,20,21-tetrahydro-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-25,25-dimethyl-15,22-dioxo-17H-5,3-([4,2]-endo-thiazolopropano[1,3]-endo-pyridazinomethanoxypropano)-1H-indol-14-yl]-2-methyl-cyclopropanecarboxamide,RMC-6236;(1S,2S)-N-[(2R,14S,18S)-1-Ethyl-18,19,20,21-tetrahydro-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-25,25-dimethyl-15,22-dioxo-17H-5,3-([4,2]-endo-thiazolopropano[1,3]-endo-pyridazinomethanoxypropano)-1H-indol-14-yl]-2-methyl-cyclopropanecarboxamide;RMC-6236RASONMULTI;Cyclopropanecarboxamide,N-[(2R,14S,18S)-1-ethyl-18,19,20,21-tetrahydro-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-25,25-dimethyl-15,22-dioxo-17H-5,3-([4,2]-endo-thiazolopropano[1,3]-endo-pyridazinomethanoxypropano)-1H-indol-14-yl]-2-methyl-,(1S,2S)-;Daraxonrasib

CAS号：2765081-21-6

分子式：C44H58N8O5S

分子量：811.05

CAS NO：2765081-21-6

EC NO：

分子式：

分子量：

别 名：RAS-IN-2;泛KRAS抑制剂;化合物 RMC-6236;(1S,2S)-N-[(2R,14S,18S)-1-乙基-18,19,20,21-四氢-2-[2-[(1S)-1-甲氧基乙基]-5-(4-甲基-1-哌嗪基)-3-吡啶基]-25,25-二甲基-15,22-二氧代-17H-5,3-([4,2]-ENDO-噻唑丙烷并[1,3]-ENDO-2-哒嗪基甲氧基丙烷)-1H-吲哚-14-基]-2-甲基环丙烷甲酰胺;(1S,2S)-N-[(2R,14S,18S)-1-乙基-18,19,20,21-四氢-2-[2-[(1S)-1-甲氧基乙基]-5-(4-甲基-1-哌嗪基)-3-吡啶基]-25,25-二甲基-15,22-二氧代-17H-5,3-([4,2]-ENDO-噻唑丙烷并[1,3]-ENDO-2-哒嗪基甲氧基丙烷)-1H-吲哚-;

结构式：